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<body class="mediawiki ltr sitedir-ltr mw-hide-empty-elt ns-0 ns-subject mw-editable page-SH2D4A rootpage-SH2D4A skin-vector action-view skin-vector-legacy"><div id="mw-page-base" class="noprint"></div>
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<h1 id="firstHeading" class="firstHeading mw-first-heading">SH2D4A</h1>
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<div id="siteSub" class="noprint">From Wikipedia, the free encyclopedia</div>
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<div id="mw-content-text" class="mw-body-content mw-content-ltr" lang="en" dir="ltr"><div class="mw-parser-output"><div class="shortdescription nomobile noexcerpt noprint searchaux" style="display:none">Protein-coding gene in the species Homo sapiens</div>
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<table class="infobox" style="width:26.4em"><tbody><tr><th colspan="4" style="text-align:center;font-size:125%;font-weight:bold">SH2D4A</th></tr><tr><td colspan="4" style="text-align:center"></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd">Identifiers</th></tr><tr><th scope="row" style="background-color:#c3fdb8"><span class="plainlinks"><a href="/wiki/Gene_nomenclature" title="Gene nomenclature">Aliases</a></span></th><td colspan="3" style="background:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.genenames.org/data/gene-symbol-report/#!/hgnc_id/26102">SH2D4A</a></span>, PPP1R38, SH2A, SH2 domain containing 4A</td></tr><tr><th scope="row" style="background-color:#c3fdb8">External IDs</th><td colspan="3" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Mendelian_Inheritance_in_Man" class="mw-redirect" title="Mendelian Inheritance in Man">OMIM</a>: <a rel="nofollow" class="external text" href="https://omim.org/entry/614968">614968</a> <a href="/wiki/Mouse_Genome_Informatics" title="Mouse Genome Informatics">MGI</a>: <a rel="nofollow" class="external text" href="http://www.informatics.jax.org/marker/MGI:1919531">1919531</a> <a href="/wiki/HomoloGene" title="HomoloGene">HomoloGene</a>: <a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=homologene&dopt=HomoloGene&list_uids=11117">11117</a> <a href="/wiki/GeneCards" title="GeneCards">GeneCards</a>: <a rel="nofollow" class="external text" href="https://www.genecards.org/cgi-bin/carddisp.pl?gene=SH2D4A">SH2D4A</a> </span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd">Gene location (<a href="/wiki/Human_genome" title="Human genome">Human</a>)</th></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/File:Ideogram_human_chromosome_8.svg" class="image" title="Chromosome 8 (human)"><img alt="Chromosome 8 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/300px-Ideogram_human_chromosome_8.svg.png" decoding="async" width="300" height="120" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/450px-Ideogram_human_chromosome_8.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/6/60/Ideogram_human_chromosome_8.svg/600px-Ideogram_human_chromosome_8.svg.png 2x" data-file-width="474" data-file-height="189" /></a></td></tr><tr><th scope="row" width="15%" style="background-color:#c3fdb8"><a href="/wiki/Chromosome" title="Chromosome">Chr.</a></th><td colspan="3" width="85%" style="background-color:#eee"><span class="plainlinks"><a href="/wiki/Chromosome_8_(human)" class="mw-redirect" title="Chromosome 8 (human)">Chromosome 8 (human)</a><sup id="cite_ref-refGRCh38Ensembl_1-0" class="reference"><a href="#cite_note-refGRCh38Ensembl-1">[1]</a></sup></span></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><div align="center"><div style="position: relative; width: 300px;"><a href="/wiki/File:Human_chromosome_8_ideogram.svg" class="image" title="Chromosome 8 (human)"><img alt="Chromosome 8 (human)" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/Human_chromosome_8_ideogram.svg/300px-Human_chromosome_8_ideogram.svg.png" decoding="async" width="300" height="58" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/37/Human_chromosome_8_ideogram.svg/450px-Human_chromosome_8_ideogram.svg.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/37/Human_chromosome_8_ideogram.svg/600px-Human_chromosome_8_ideogram.svg.png 2x" data-file-width="1125" data-file-height="216" /></a><div style="position: absolute; left: 33.824118084399px; top: 2px; padding: 0;"><a href="/wiki/File:HSR_1996_II_3.5e.svg" class="image" title="Genomic location for SH2D4A"><img alt="Genomic lo
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<ul><li>secondary oocyte<br /></li>
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<li>Achilles tendon<br /></li>
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<li>amniotic fluid<br /></li>
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<li>palpebral conjunctiva<br /></li>
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<li>pylorus<br /></li>
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<li>parotid gland<br /></li>
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<li>Right lobe of liver<br /></li>
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<li>pancreatic epithelial cell<br /></li>
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<li>cardia<br /></li>
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<li>vena cava</li></ul></div></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="https://bgee.org/?page=gene&gene_id=ENSG00000104611">More reference expression data</a></span></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a rel="nofollow" class="external text" href="http://biogps.org/">BioGPS</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><td colspan="4" style="text-align:center;background-color:#eee"><a href="/wiki/File:PBB_GE_SH2D4A_219749_at_fs.png" class="image"><img alt="PBB GE SH2D4A 219749 at fs.png" src="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PBB_GE_SH2D4A_219749_at_fs.png/250px-PBB_GE_SH2D4A_219749_at_fs.png" decoding="async" width="250" height="181" srcset="//upload.wikimedia.org/wikipedia/commons/thumb/3/36/PBB_GE_SH2D4A_219749_at_fs.png/375px-PBB_GE_SH2D4A_219749_at_fs.png 1.5x, //upload.wikimedia.org/wikipedia/commons/thumb/3/36/PBB_GE_SH2D4A_219749_at_fs.png/500px-PBB_GE_SH2D4A_219749_at_fs.png 2x" data-file-width="732" data-file-height="530" /></a></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><span class="plainlinks"><a rel="nofollow" class="external text" href="http://biogps.org/gene/63898/">More reference expression data</a></span></td></tr></tbody></table></td></tr></tbody></table></td></tr><tr><td colspan="4" style="text-align:center;background-color:#eee"><table class="collapsible collapsed" style="padding:0;border:none;margin:0;width:100%;text-align:left"><tbody><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Gene_ontology" class="mw-redirect" title="Gene ontology">Gene ontology</a></th></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Molecular function</td><td style="background-color:#eee"><div class="plainlinks">
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<li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005515,">GO:0001948 protein binding</a></li>
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<li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0019902">phosphatase binding</a></li>
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</div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Cellular component</td><td style="background-color:#eee"><div class="plainlinks">
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<ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005737">cytoplasm</a></li>
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<li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0005829">cytosol</a></li></ul>
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</div></td></tr><tr><td style="background-color:#c3fdb8;font-weight:bold">Biological process</td><td style="background-color:#eee"><div class="plainlinks">
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<ul><li><a rel="nofollow" class="external text" href="http://amigo.geneontology.org/amigo/term/GO:0010923">negative regulation of phosphatase activity</a></li></ul>
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</div></td></tr><tr><td colspan="4" style="background-color:#eee;text-align:center">Sources:<a rel="nofollow" class="external text" href="http://amigo.geneontology.org/">Amigo</a> / <a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/QuickGO/">QuickGO</a></td></tr></tbody></table></td></tr><tr><th colspan="4" style="text-align:center;background-color:#ddd"><a href="/wiki/Orthologs" class="mw-redirect" title="Orthologs">Orthologs</a></th></tr><tr><th scope="row" style="background-color:#c3fdb8">Species</th><td><b>Human</b></td><td><b>Mouse</b></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Entrez" title="Entrez">Entrez</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=63898&rn=1">63898</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=retrieve&dopt=default&list_uids=72281&rn=1">72281</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/Ensembl" class="mw-redirect" title="Ensembl">Ensembl</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Homo_sapiens/geneview?gene=ENSG00000104611;db=core">ENSG00000104611</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="http://www.ensembl.org/Mus_musculus/geneview?gene=ENSMUSG00000053886;db=core">ENSMUSG00000053886</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8"><a href="/wiki/UniProt" title="UniProt">UniProt</a></th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9H788">Q9H788</a></p></td></tr></tbody></table></td><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1"><span class="plainlinks"></span></th></tr><tr><td colspan="1"><p class="plainlinks"><a rel="nofollow" class="external text" href="https://www.uniprot.org/uniprot/Q9D7V1">Q9D7V1</a></p></td></tr></tbody></table></td></tr><tr><th scope="row" style="background-color:#c3fdb8">RefSeq (mRNA)</th><td><table class="none" style="padding:0;border:none;margin:0;width:100%;text-align:right"><tbody><tr><th colspan="1" class="plainlinks"></th></tr><tr><td colspan="1"><p><span class="plainlinks"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001174159">NM_001174159</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001174160">NM_001174160</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_022071">NM_022071</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001363110">NM_001363110</a><br /><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/entrez/viewer.fcgi?val=NM_001363111">NM_001
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<p><b>SH2 domain-containing protein 4A</b> is a <a href="/wiki/Protein" title="Protein">protein</a> that in humans is encoded by the <i>SH2D4A</i> <a href="/wiki/Gene" title="Gene">gene</a>.<sup id="cite_ref-entrez_5-0" class="reference"><a href="#cite_note-entrez-5">[5]</a></sup>
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</p>
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<h2><span class="mw-headline" id="Interactions">Interactions</span><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SH2D4A&action=edit&section=1" title="Edit section: Interactions">edit</a><span class="mw-editsection-bracket">]</span></span></h2>
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<p>SH2D4A has been shown to <a href="/wiki/Protein-protein_interaction" class="mw-redirect" title="Protein-protein interaction">interact</a> with <a href="/wiki/MAGEA11" title="MAGEA11">MAGEA11</a>.<sup id="cite_ref-pmid16189514_6-0" class="reference"><a href="#cite_note-pmid16189514-6">[6]</a></sup>
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</p>
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<h2><span class="mw-headline" id="References">References</span><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SH2D4A&action=edit&section=2" title="Edit section: References">edit</a><span class="mw-editsection-bracket">]</span></span></h2>
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<li id="cite_note-refGRCh38Ensembl-1"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCh38Ensembl_1-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCh38Ensembl_1-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Homo_sapiens/Gene/Summary?db=core;g=ENSG00000104611">GRCh38: Ensembl release 89: ENSG00000104611</a> - <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span>
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<li id="cite_note-refGRCm38Ensembl-2"><span class="mw-cite-backlink">^ <a href="#cite_ref-refGRCm38Ensembl_2-0"><sup><i><b>a</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-1"><sup><i><b>b</b></i></sup></a> <a href="#cite_ref-refGRCm38Ensembl_2-2"><sup><i><b>c</b></i></sup></a></span> <span class="reference-text"><a rel="nofollow" class="external text" href="http://May2017.archive.ensembl.org/Mus_musculus/Gene/Summary?db=core;g=ENSMUSG00000053886">GRCm38: Ensembl release 89: ENSMUSG00000053886</a> - <a href="/wiki/Ensembl_genome_database_project" title="Ensembl genome database project">Ensembl</a>, May 2017</span>
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<li id="cite_note-3"><span class="mw-cite-backlink"><b><a href="#cite_ref-3">^</a></b></span> <span class="reference-text"><style data-mw-deduplicate="TemplateStyles:r1067248974">.mw-parser-output cite.citation{font-style:inherit;word-wrap:break-word}.mw-parser-output .citation q{quotes:"\"""\"""'""'"}.mw-parser-output .citation:target{background-color:rgba(0,127,255,0.133)}.mw-parser-output .id-lock-free a,.mw-parser-output .citation .cs1-lock-free a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/6/65/Lock-green.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-limited a,.mw-parser-output .id-lock-registration a,.mw-parser-output .citation .cs1-lock-limited a,.mw-parser-output .citation .cs1-lock-registration a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/d/d6/Lock-gray-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .id-lock-subscription a,.mw-parser-output .citation .cs1-lock-subscription a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/a/aa/Lock-red-alt-2.svg")right 0.1em center/9px no-repeat}.mw-parser-output .cs1-ws-icon a{background:linear-gradient(transparent,transparent),url("//upload.wikimedia.org/wikipedia/commons/4/4c/Wikisource-logo.svg")right 0.1em center/12px no-repeat}.mw-parser-output .cs1-code{color:inherit;background:inherit;border:none;padding:inherit}.mw-parser-output .cs1-hidden-error{display:none;color:#d33}.mw-parser-output .cs1-visible-error{color:#d33}.mw-parser-output .cs1-maint{display:none;color:#3a3;margin-left:0.3em}.mw-parser-output .cs1-format{font-size:95%}.mw-parser-output .cs1-kern-left{padding-left:0.2em}.mw-parser-output .cs1-kern-right{padding-right:0.2em}.mw-parser-output .citation .mw-selflink{font-weight:inherit}</style><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=63898">"Human PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Human+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D63898&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></span>
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<li id="cite_note-4"><span class="mw-cite-backlink"><b><a href="#cite_ref-4">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&cmd=Link&LinkName=gene_pubmed&from_uid=72281">"Mouse PubMed Reference:"</a>. <i>National Center for Biotechnology Information, U.S. National Library of Medicine</i>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=unknown&rft.jtitle=National+Center+for+Biotechnology+Information%2C+U.S.+National+Library+of+Medicine&rft.atitle=Mouse+PubMed+Reference%3A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3Fdb%3Dgene%26cmd%3DLink%26LinkName%3Dgene_pubmed%26from_uid%3D72281&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></span>
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<li id="cite_note-entrez-5"><span class="mw-cite-backlink"><b><a href="#cite_ref-entrez_5-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite class="citation web cs1"><a rel="nofollow" class="external text" href="https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=63898">"Entrez Gene: SH2D4A SH2 domain containing 4A"</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Abook&rft.genre=unknown&rft.btitle=Entrez+Gene%3A+SH2D4A+SH2+domain+containing+4A&rft_id=https%3A%2F%2Fwww.ncbi.nlm.nih.gov%2Fsites%2Fentrez%3FDb%3Dgene%26Cmd%3DShowDetailView%26TermToSearch%3D63898&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></span>
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<li id="cite_note-pmid16189514-6"><span class="mw-cite-backlink"><b><a href="#cite_ref-pmid16189514_6-0">^</a></b></span> <span class="reference-text"><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFRualVenkatesanHaoHirozane-Kishikawa2005" class="citation journal cs1">Rual JF, Venkatesan K, Hao T, Hirozane-Kishikawa T, Dricot A, Li N, Berriz GF, Gibbons FD, Dreze M, Ayivi-Guedehoussou N, Klitgord N, Simon C, Boxem M, Milstein S, Rosenberg J, Goldberg DS, Zhang LV, Wong SL, Franklin G, Li S, Albala JS, Lim J, Fraughton C, Llamosas E, Cevik S, Bex C, Lamesch P, Sikorski RS, Vandenhaute J, Zoghbi HY, Smolyar A, Bosak S, Sequerra R, Doucette-Stamm L, Cusick ME, Hill DE, Roth FP, Vidal M (October 2005). "Towards a proteome-scale map of the human protein-protein interaction network". <i>Nature</i>. <b>437</b> (7062): 1173–1178. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2005Natur.437.1173R">2005Natur.437.1173R</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnature04209">10.1038/nature04209</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/16189514">16189514</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:4427026">4427026</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nature&rft.atitle=Towards+a+proteome-scale+map+of+the+human+protein-protein+interaction+network&rft.volume=437&rft.issue=7062&rft.pages=1173-1178&rft.date=2005-10&rft_id=info%3Adoi%2F10.1038%2Fnature04209&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A4427026%23id-name%3DS2CID&rft_id=info%3Apmid%2F16189514&rft_id=info%3Abibcode%2F2005Natur.437.1173R&rft.aulast=Rual&rft.aufirst=JF&rft.au=Venkatesan%2C+K&rft.au=Hao%2C+T&rft.au=Hirozane-Kishikawa%2C+T&rft.au=Dricot%2C+A&rft.au=Li%2C+N&rft.au=Berriz%2C+GF&rft.au=Gibbons%2C+FD&rft.au=Dreze%2C+M&rft.au=Ayivi-Guedehoussou%2C+N&rft.au=Klitgord%2C+N&rft.au=Simon%2C+C&rft.au=Boxem%2C+M&rft.au=Milstein%2C+S&rft.au=Rosenberg%2C+J&rft.au=Goldberg%2C+DS&rft.au=Zhang%2C+LV&rft.au=Wong%2C+SL&rft.au=Franklin%2C+G&rft.au=Li%2C+S&rft.au=Albala%2C+JS&rft.au=Lim%2C+J&rft.au=Fraughton%2C+C&rft.au=Llamosas%2C+E&rft.au=Cevik%2C+S&rft.au=Bex%2C+C&rft.au=Lamesch%2C+P&rft.au=Sikorski%2C+RS&rft.au=Vandenhaute%2C+J&rft.au=Zoghbi%2C+HY&rft.au=Smolyar%2C+A&rft.au=Bosak%2C+S&rft.au=Sequerra%2C+R&rft.au=Doucette-Stamm%2C+L&rft.au=Cusick%2C+ME&rft.au=Hill%2C+DE&rft.au=Roth%2C+FP&rft.au=Vidal%2C+M&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></span>
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<h2><span class="mw-headline" id="Further_reading">Further reading</span><span class="mw-editsection"><span class="mw-editsection-bracket">[</span><a href="/w/index.php?title=SH2D4A&action=edit&section=3" title="Edit section: Further reading">edit</a><span class="mw-editsection-bracket">]</span></span></h2>
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<style data-mw-deduplicate="TemplateStyles:r1054258005">.mw-parser-output .refbegin{font-size:90%;margin-bottom:0.5em}.mw-parser-output .refbegin-hanging-indents>ul{margin-left:0}.mw-parser-output .refbegin-hanging-indents>ul>li{margin-left:0;padding-left:3.2em;text-indent:-3.2em}.mw-parser-output .refbegin-hanging-indents ul,.mw-parser-output .refbegin-hanging-indents ul li{list-style:none}@media(max-width:720px){.mw-parser-output .refbegin-hanging-indents>ul>li{padding-left:1.6em;text-indent:-1.6em}}.mw-parser-output .refbegin-columns{margin-top:0.3em}.mw-parser-output .refbegin-columns ul{margin-top:0}.mw-parser-output .refbegin-columns li{page-break-inside:avoid;break-inside:avoid-column}</style><div class="refbegin refbegin-columns references-column-count references-column-count-2" style="column-count: 2;">
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<ul><li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFMaruyamaSugano1994" class="citation journal cs1">Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". <i>Gene</i>. <b>138</b> (1–2): 171–174. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2F0378-1119%2894%2990802-8">10.1016/0378-1119(94)90802-8</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/8125298">8125298</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Gene&rft.atitle=Oligo-capping%3A+a+simple+method+to+replace+the+cap+structure+of+eukaryotic+mRNAs+with+oligoribonucleotides.&rft.volume=138&rft.issue=1%E2%80%932&rft.pages=171-174&rft.date=1994&rft_id=info%3Adoi%2F10.1016%2F0378-1119%2894%2990802-8&rft_id=info%3Apmid%2F8125298&rft.aulast=Maruyama&rft.aufirst=K&rft.au=Sugano%2C+S&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFSuzukiYoshitomo-NakagawaMaruyama1997" class="citation journal cs1">Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". <i>Gene</i>. <b>200</b> (1–2): 149–156. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1016%2FS0378-1119%2897%2900411-3">10.1016/S0378-1119(97)00411-3</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/9373149">9373149</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Gene&rft.atitle=Construction+and+characterization+of+a+full+length-enriched+and+a+5%27-end-enriched+cDNA+library.&rft.volume=200&rft.issue=1%E2%80%932&rft.pages=149-156&rft.date=1997&rft_id=info%3Adoi%2F10.1016%2FS0378-1119%2897%2900411-3&rft_id=info%3Apmid%2F9373149&rft.aulast=Suzuki&rft.aufirst=Y&rft.au=Yoshitomo-Nakagawa%2C+K&rft.au=Maruyama%2C+K&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFDaiZhaoDing2003" class="citation journal cs1">Dai S, Zhao Y, Ding Q (2003). "[A novel member of SH(2) signaling protein family: cloning and characterization of SH(2)A gene]". <i>Zhonghua Yi Xue Yi Chuan Xue Za Zhi</i>. <b>19</b> (6): 458–462. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/12476414">12476414</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Zhonghua+Yi+Xue+Yi+Chuan+Xue+Za+Zhi&rft.atitle=%5BA+novel+member+of+SH%282%29+signaling+protein+family%3A+cloning+and+characterization+of+SH%282%29A+gene%5D&rft.volume=19&rft.issue=6&rft.pages=458-462&rft.date=2003&rft_id=info%3Apmid%2F12476414&rft.aulast=Dai&rft.aufirst=S&rft.au=Zhao%2C+Y&rft.au=Ding%2C+Q&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFStrausbergFeingoldGrouse2003" class="citation journal cs1">Strausberg RL, Feingold EA, Grouse LH, et al. (2003). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC139241">"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences"</a>. <i>Proc. Natl. Acad. Sci. U.S.A</i>. <b>99</b> (26): 16899–16903. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.242603899">10.1073/pnas.242603899</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC139241">139241</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/12477932">12477932</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proc.+Natl.+Acad.+Sci.+U.S.A.&rft.atitle=Generation+and+initial+analysis+of+more+than+15%2C000+full-length+human+and+mouse+cDNA+sequences.&rft.volume=99&rft.issue=26&rft.pages=16899-16903&rft.date=2003&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC139241%23id-name%3DPMC&rft_id=info%3Apmid%2F12477932&rft_id=info%3Adoi%2F10.1073%2Fpnas.242603899&rft.aulast=Strausberg&rft.aufirst=RL&rft.au=Feingold%2C+EA&rft.au=Grouse%2C+LH&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC139241&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFOtaSuzukiNishikawa2004" class="citation journal cs1">Ota T, Suzuki Y, Nishikawa T, et al. (2004). <a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fng1285">"Complete sequencing and characterization of 21,243 full-length human cDNAs"</a>. <i>Nat. Genet</i>. <b>36</b> (1): 40–45. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fng1285">10.1038/ng1285</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/14702039">14702039</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Genet.&rft.atitle=Complete+sequencing+and+characterization+of+21%2C243+full-length+human+cDNAs.&rft.volume=36&rft.issue=1&rft.pages=40-45&rft.date=2004&rft_id=info%3Adoi%2F10.1038%2Fng1285&rft_id=info%3Apmid%2F14702039&rft.aulast=Ota&rft.aufirst=T&rft.au=Suzuki%2C+Y&rft.au=Nishikawa%2C+T&rft_id=%2F%2Fdoi.org%2F10.1038%252Fng1285&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFBeausoleilJedrychowskiSchwartz2004" class="citation journal cs1">Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC514446">"Large-scale characterization of HeLa cell nuclear phosphoproteins"</a>. <i>Proc. Natl. Acad. Sci. U.S.A</i>. <b>101</b> (33): 12130–12135. <a href="/wiki/Bibcode_(identifier)" class="mw-redirect" title="Bibcode (identifier)">Bibcode</a>:<a rel="nofollow" class="external text" href="https://ui.adsabs.harvard.edu/abs/2004PNAS..10112130B">2004PNAS..10112130B</a>. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="https://doi.org/10.1073%2Fpnas.0404720101">10.1073/pnas.0404720101</a></span>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC514446">514446</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/15302935">15302935</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Proc.+Natl.+Acad.+Sci.+U.S.A.&rft.atitle=Large-scale+characterization+of+HeLa+cell+nuclear+phosphoproteins.&rft.volume=101&rft.issue=33&rft.pages=12130-12135&rft.date=2004&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC514446%23id-name%3DPMC&rft_id=info%3Apmid%2F15302935&rft_id=info%3Adoi%2F10.1073%2Fpnas.0404720101&rft_id=info%3Abibcode%2F2004PNAS..10112130B&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Jedrychowski%2C+M&rft.au=Schwartz%2C+D&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC514446&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFGerhardWagnerFeingold2004" class="citation journal cs1">Gerhard DS, Wagner L, Feingold EA, et al. (2004). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC528928">"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)"</a>. <i>Genome Res</i>. <b>14</b> (10B): 2121–2127. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1101%2Fgr.2596504">10.1101/gr.2596504</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC528928">528928</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/15489334">15489334</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Genome+Res.&rft.atitle=The+status%2C+quality%2C+and+expansion+of+the+NIH+full-length+cDNA+project%3A+the+Mammalian+Gene+Collection+%28MGC%29.&rft.volume=14&rft.issue=10B&rft.pages=2121-2127&rft.date=2004&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC528928%23id-name%3DPMC&rft_id=info%3Apmid%2F15489334&rft_id=info%3Adoi%2F10.1101%2Fgr.2596504&rft.aulast=Gerhard&rft.aufirst=DS&rft.au=Wagner%2C+L&rft.au=Feingold%2C+EA&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC528928&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFBeausoleilVillénGerber2006" class="citation journal cs1">Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". <i>Nat. Biotechnol</i>. <b>24</b> (10): 1285–1292. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fnbt1240">10.1038/nbt1240</a>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/16964243">16964243</a>. <a href="/wiki/S2CID_(identifier)" class="mw-redirect" title="S2CID (identifier)">S2CID</a> <a rel="nofollow" class="external text" href="https://api.semanticscholar.org/CorpusID:14294292">14294292</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Nat.+Biotechnol.&rft.atitle=A+probability-based+approach+for+high-throughput+protein+phosphorylation+analysis+and+site+localization.&rft.volume=24&rft.issue=10&rft.pages=1285-1292&rft.date=2006&rft_id=https%3A%2F%2Fapi.semanticscholar.org%2FCorpusID%3A14294292%23id-name%3DS2CID&rft_id=info%3Apmid%2F16964243&rft_id=info%3Adoi%2F10.1038%2Fnbt1240&rft.aulast=Beausoleil&rft.aufirst=SA&rft.au=Vill%C3%A9n%2C+J&rft.au=Gerber%2C+SA&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li>
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<li><link rel="mw-deduplicated-inline-style" href="mw-data:TemplateStyles:r1067248974"/><cite id="CITEREFEwingChuElisma2007" class="citation journal cs1">Ewing RM, Chu P, Elisma F, et al. (2007). <a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1847948">"Large-scale mapping of human protein-protein interactions by mass spectrometry"</a>. <i>Mol. Syst. Biol</i>. <b>3</b> (1): 89. <a href="/wiki/Doi_(identifier)" class="mw-redirect" title="Doi (identifier)">doi</a>:<a rel="nofollow" class="external text" href="https://doi.org/10.1038%2Fmsb4100134">10.1038/msb4100134</a>. <a href="/wiki/PMC_(identifier)" class="mw-redirect" title="PMC (identifier)">PMC</a> <span class="cs1-lock-free" title="Freely accessible"><a rel="nofollow" class="external text" href="//www.ncbi.nlm.nih.gov/pmc/articles/PMC1847948">1847948</a></span>. <a href="/wiki/PMID_(identifier)" class="mw-redirect" title="PMID (identifier)">PMID</a> <a rel="nofollow" class="external text" href="//pubmed.ncbi.nlm.nih.gov/17353931">17353931</a>.</cite><span title="ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.jtitle=Mol.+Syst.+Biol.&rft.atitle=Large-scale+mapping+of+human+protein-protein+interactions+by+mass+spectrometry.&rft.volume=3&rft.issue=1&rft.pages=89&rft.date=2007&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1847948%23id-name%3DPMC&rft_id=info%3Apmid%2F17353931&rft_id=info%3Adoi%2F10.1038%2Fmsb4100134&rft.aulast=Ewing&rft.aufirst=RM&rft.au=Chu%2C+P&rft.au=Elisma%2C+F&rft_id=%2F%2Fwww.ncbi.nlm.nih.gov%2Fpmc%2Farticles%2FPMC1847948&rfr_id=info%3Asid%2Fen.wikipedia.org%3ASH2D4A" class="Z3988"></span></li></ul>
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